{"product_id":"tamoxifen-citrate","title":"Tamoxifen Citrate","description":"\u003cp\u003e\u003cstrong\u003eProduct Name:\u003c\/strong\u003e Tamoxifen Citrate\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Liquid Solution (30mL)\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 20mg\/mL\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 98% (HPLC Verified)\u003c\/p\u003e\u003ch3\u003eProduct Description\u003c\/h3\u003e\u003cp\u003eTamoxifen Citrate is one of the most well-established selective estrogen receptor modulators (SERMs) in pharmacological research, with over five decades of clinical use and investigation. It acts as a competitive antagonist of estrogen at receptor sites in breast tissue whilst exhibiting partial agonist activity in bone, the uterus, and the cardiovascular system. Tamoxifen's mechanism involves binding to the estrogen receptor (ER), preventing the conformational change necessary for co-activator recruitment and transcriptional activation of estrogen-responsive genes. In endocrine research, tamoxifen is extensively used to study HPG axis modulation, as its hypothalamic estrogen receptor antagonism stimulates increased GnRH pulsatility and subsequent gonadotropin (LH\/FSH) release. It is also widely used in conditional gene knockout systems (CreERT2) where tamoxifen-inducible Cre recombinase enables temporal control of gene deletion in research models. This product is provided exclusively for scientific research and laboratory use.\u003c\/p\u003e\u003ch3\u003eStorage \u0026amp; Handling\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eStore at room temperature (15–25°C) in a cool, dry place\u003c\/li\u003e\n\u003cli\u003eKeep away from direct sunlight and heat sources\u003c\/li\u003e\n\u003cli\u003eEnsure the cap is tightly sealed after each use\u003c\/li\u003e\n\u003cli\u003eDo not refrigerate or freeze liquid solutions unless specified\u003c\/li\u003e\n\u003cli\u003eShelf life: 24 months from date of manufacture when stored correctly\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children and untrained personnel\u003c\/li\u003e\n\u003cli\u003eHandle with appropriate laboratory safety equipment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eUsage Guidelines\u003c\/h3\u003e\u003cp\u003eThis product is supplied as a precisely dosed liquid solution for convenient and accurate measurement in research applications. Use calibrated measuring equipment (oral syringe or graduated pipette) for precise dosing. Refer to the included Certificate of Analysis for batch-specific purity and identity data.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This product is intended for research and laboratory use only. It is not a dietary supplement, food product, or medicine. Not intended for human consumption. All purchasers must confirm they are acquiring this product for legitimate research purposes only. Product imagery is for illustrative purposes only and actual product packaging and branding may vary. All products are verified to ≥98% purity via HPLC analysis.\u003c\/p\u003e","brand":"SARMS UK","offers":[{"title":"Default","offer_id":57286195052879,"sku":"SARM-TAMOX","price":34.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0983\/8598\/5871\/files\/TamoxifenCitrate.png?v=1774086431","url":"https:\/\/sarmsuk.com\/products\/tamoxifen-citrate","provider":"SARMs UK","version":"1.0","type":"link"}