{"product_id":"5-amino-1mq","title":"5-Amino-1MQ","description":"\u003cp\u003e\u003cstrong\u003eProduct Name:\u003c\/strong\u003e 5-Amino-1MQ\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Liquid Solution (30mL)\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 50mg\/mL\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 98% (HPLC Verified)\u003c\/p\u003e\u003ch3\u003eProduct Description\u003c\/h3\u003e\u003cp\u003e5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that has emerged as a significant target in metabolic and obesity research. NNMT catalyses the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor, and its overexpression has been strongly associated with adiposity, insulin resistance, and metabolic dysfunction. Research published in Biochemical Pharmacology has demonstrated that inhibition of NNMT by 5-Amino-1MQ can increase intracellular NAD+ and SAM concentrations, enhance cellular energy expenditure, and reduce lipid accumulation in adipocyte models. Preclinical studies in diet-induced obesity models have shown significant reductions in body weight, fat mass, and plasma cholesterol levels without affecting food intake. 5-Amino-1MQ represents a novel approach to metabolic research targeting the methylation-energy expenditure axis. This product is provided exclusively for scientific research and laboratory use.\u003c\/p\u003e\u003ch3\u003eStorage \u0026amp; Handling\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eStore at room temperature (15–25°C) in a cool, dry place\u003c\/li\u003e\n\u003cli\u003eKeep away from direct sunlight and heat sources\u003c\/li\u003e\n\u003cli\u003eEnsure the cap is tightly sealed after each use\u003c\/li\u003e\n\u003cli\u003eDo not refrigerate or freeze liquid solutions unless specified\u003c\/li\u003e\n\u003cli\u003eShelf life: 24 months from date of manufacture when stored correctly\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children and untrained personnel\u003c\/li\u003e\n\u003cli\u003eHandle with appropriate laboratory safety equipment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eUsage Guidelines\u003c\/h3\u003e\u003cp\u003eThis product is supplied as a precisely dosed liquid solution for convenient and accurate measurement in research applications. Use calibrated measuring equipment (oral syringe or graduated pipette) for precise dosing. Refer to the included Certificate of Analysis for batch-specific purity and identity data.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This product is intended for research and laboratory use only. It is not a dietary supplement, food product, or medicine. Not intended for human consumption. All purchasers must confirm they are acquiring this product for legitimate research purposes only. Product imagery is for illustrative purposes only and actual product packaging and branding may vary. All products are verified to ≥98% purity via HPLC analysis.\u003c\/p\u003e","brand":"SARMS UK","offers":[{"title":"Default","offer_id":57286195085647,"sku":"SARM-5A1MQ","price":54.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0983\/8598\/5871\/files\/5-Amino-1mq.png?v=1774086417","url":"https:\/\/sarmsuk.com\/products\/5-amino-1mq","provider":"SARMs UK","version":"1.0","type":"link"}